‘Fatal case of sorafenib-associated hepatotoxicity in the adjuvant treatment of a patient with Renal Cell Carcinoma’ - Response to reviewers comments
نویسندگان
چکیده
Benjamin P Fairfax ([email protected]) Sarah Pratap ([email protected]) Ian SD Roberts ([email protected]) Jane Collier ([email protected]) Rick Kaplan ([email protected]) Angela M Meade ([email protected]) Alistair W Ritchie ([email protected]) Tim Eisen ([email protected]) Valentine Macaulay ([email protected]) Andrew Protheroe ([email protected])
منابع مشابه
Fatal case of Sorafenib-associated hepatotoxicity in the adjuvant treatment of a patient with Renal Cell Carcinoma
Sorafenib is an orally available inhibitor of multiple kinases including PDGF β and VEGF receptors and Raf kinase licensed for the treatment of advanced renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). Current evidencebased management of individuals with localized RCC treated by nephrectomy is limited to surveillance-based follow up only. The SORCE trial aims to investigate whethe...
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Objective(s): Hepatocellular carcinoma (HCC) is one of the most significant health condition around the world. As the only curative therapies, liver transplantation and surgical resection are the clinical treatments of HCC. Due to the systemic toxicity and severe side effects of these treatments, it is vital to establish new therapeutic approaches. The present study ai...
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Background and Objective: Esophageal cancer especially squamous cell carcinoma (SCC) is one of the most common gastro intestinal malignancies in north part of Iran (Khorasan). The standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. Then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. Sever...
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Thyroid gland metastatic tumors are rare in clinical practice. Clear cell RCC is one of common metastatic tumors to thyroid. We here reported a case of incidentally found clear cell renal carcinoma metastasis to the thyroid gland 3 years after nephrectomy, in the thyroidectomy procedure performed for the patient due to the thyroid enlargement caused by multinodular goiter. A 65-year-old Iranian...
متن کاملMetastatic Renal cell Carcinoma Presenting as a clear-cell Tumor in Tongue: A Case Report
Introduction: Metastatic lesions of the oral cavity are extremely rare, accounting for approximately 1% of all malignant oral tumors. The most common primary sources of metastatic tumors in the oral region are, from the most to the least common, the breast, lung, kidney, bone, and colon. Renal cell carcinoma accounts for nearly 3% of all adult malignancies. It usually metastasizes to the lungs,...
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تاریخ انتشار 2012